Student Projects


We are looking for motivated bachelor and master students with background of physics, biology, or chemistry. Many exciting projects are available for TU Delft (nanobiology, applied physics, and LST) students. The projects are also open to students from outside of TU Delft.


High throughput single-molecule detection

We have a project that will make a breakthrough in single-molecule biophysics. By coupling Illuminia DNA sequencing techniques with single-molecule fluorescence, you will make a platform for observing thousands to millions of different DNA sequences. This technique will be used for studying CRISPR and microRNA. 

Melis Teke (LST)

Frank Brandenburg (applied physics)

Roy Simons (LST)

Marjolein Kerstjens (LST)

Berkalp Doğaner (nanobiology)

Ivo Severins (applied physics) (publications)

Single-molecule protein sequencing

You will develop a single‐molecule protein sequencer using single-molecule fluorescence and nano mass sensor (graphene). These will become the first single-molecule protein sequencers ever realized.

Raman van Wee (nanobiology)

Tygo Huurnink (nanobiology)

Anna Hartendorp (nanobiology)

Virgil Woerdings (nanobiology)

Isabell Trinh (nanobiology)

Chun Heung Wong (applied physics)

Nicola Bellotto (nanobiotechnology, Italy)

Lois van der Drift (nanobiology)

Nathalie Worp (LST) (publications)

Louis-Marie Chauveau (biotechnology, France)

Mike Filius (biomole. sciences, VU) (publications)

Yao Yao (bioinformatics) (publications)

Mees de Graaf (LST)

CRISPR (genome editing)

You will investigate how CRISPR targets viral genome. You will study this mechanism using single-molecule fluorescence.  Your study will make a breakthrough for advancing genome editing tools. 

Pim America (nanobiology)

Rodrigo Gonzalez (nanobiology)

David Hueting (nanobiology)

Rochelle Niemeijer (nanobiology)

Sabina Colombo (industrial biotechnology, Italy)

Justine Tang (biomedical sciences, VU)

Erwin Erdem (nanobiology)

Tim Allertz (nanobiology)

Nick de Lange (nanobiology)

RNA interference

You will investigate how microRNA is generated and finds its target RNA. You will study this mechanism using single-molecule fluorescence and computer simulation. The outcome of your study will be used for improving the efficiency of RNA interference for therapeutics.

Anne-Wietje Zwijnen (nanobiology)

Ferdy Lambregtse (LST)

Dieuwertje Drexhage (LST)

Jasper van Lopik (nanobiology) (publications)

Melissa Kerver (biomedical sciences, VU)

Abidemi Junaid (biomolecular sciences, VU)

Maxime den Ridder (LST)

Sweeny Chauhan (Germany) (publications)

It was memorable Abidemi Junaid, a master student

"I learned a lot about using interdisciplinary approaches. I had a taste of what it means to work as a PhD student, which involves hard work, creativity and enjoyment. My lab mates were social, open and happy about their work. These things made my internship fun. The project that I did was cool. (I often brag about it when people ask for my work experience). It was the first project that I had the opportunity to collaborate with another department. This was useful for me because my PhD project is a collaboration of three parties."

Accomplished my goals

Nick de Lange, a bachelor student

"This was a great opportunity to finally use my prior knowledge for an interesting project. I could also get hands-on experience. I found the lab was a great place to accomplish my goals, and the lab members were very helpful."

Felt excited and proud to work

Yao Yao, a master student

"My bioinformatics project was a part of a much bigger and ambitious one that would save the world. I found the lab lively and members friendly and rigorous. I was glad that I could meet my supervisors at least once per week. I developed an interest in wet lab work during my MEP and was given an opportunity to work in the wet lab after my MEP."

A multidisciplinary field

Ivo Severins, a master student

"My supervisor explained everything clearly and answered my questions patiently. There was always room for discussion, and I could put forward my own ideas and suggestions. There is a nice, friendly and open atmosphere in the lab, and people are always ready to help. This project was a great opportunity to work in a multidisciplinary field, combining both physical and biological research."

Leading a project on my own

Maxime den Ridder, a bachelor student

"I had a chance to improve my wet lab skills. I learned how to overexpress, label and purify proteins. It was also interesting to learn about single-molecule studies and to see how useful it is for tracking dynamic cellular processes. I was asked to take responsibility for my project (planning experiments and analyzing results) while I was always able to discuss with my supervisors. Everybody in the lab was also always willing to answer any of my questions."

Industry internship

TNO for single-molecule protein sequencing (a master project only)



Early embryo mechanics

Esmée Adegeest (nanobiology)

Soufian Lemkaddem (applied physics)

Learned to have fun doing science

Sweeny Chauhan, a bachelor student

"It is till date my best experience in a lab. I was able to learn a lot, not just regarding lab techniques but also for a scientific career. From the starting I was allowed to plan and execute my projects independently. I had great supervisors who enjoyed teaching and always helped me out with questions and doubts. I was able to improve my skills, ranging from wet lab techniques to presentations and critical questioning. Overall it was a memorable experience. I did not only gain a lot of experience and knowledge but also learned to have fun doing science. I would choose any opportunity to again work here."

Opportunity to develop yourself!

Soufian Lemkaddem, a master student

"It was a great opportunity to develop my experimental skills. I got a lot of responsibility, but at the same time I was supervised at the right moments. The lab members stimulated me in a polite and positive way during my research, and that gave me positive energy to excellence in my work.  We also had fun inside and outside the lab.  The hard working and good supervision resulted in a great grade and a completely new setup--ready to be used for promising research by new students!"