Next Generation Single-Molecule Biophysics
CHIRLMIN JOO LAB
Using next-generation single-molecule fluorescence techniques, we investigate how small regulatory RNA mediates gene silencing (RNA interference) and anti-viral defense (CRISPR immunity and beyond). We develop single-molecule protein sequencing techniques for advanced proteomics analysis. We organized conferences in 2017, 2019, 2022 .
KEY PUBLICATIONS
Severins, Joo, van Noort, "Exploring molecular biology in sequence space: The road to next-generation single-molecule biophysics", Molecular Cell (2022)
Alfaro et al, "The emerging landscape of single-molecule protein sequencing technologies" Nature Methods (2021)
Filius, Kim, Severins, Joo "High-resolution single-molecule FRET via DNA eXchange" Nano Letters (2021)
Kim, Loeff, Colombo, Jergic, Brouns, Joo "Selective loading and processing of prespacers for precise CRISPR adaptation" Nature (2020) (animation)
Cui, Klein, Hegge, Chandradoss, van der Oost, Depken, Joo "Argonaute bypasses cellular obstacles without hindrance during target search" Nature Communications (2019)
LAB NEWS
Feb 2024 Carolien gives a talk in Biophysical Society Meeting
Jan 2023 Koushik gives a talk in Single-Molecule Biophysics Les Houches
Dec 2023 Chirlmin gives a talk in CNRS
Dec 2023 Chirlmin gives a talk in imec
Dec 2023 Chirlmin gives a talk in NKI
Nov 2023 Bhagyashree received EMBO Travel Grant
Nov 2023 Our paper has been accepted by Nature Nanotechnology
Oct 2023 Ivo gives a talk in NWO Biophysics
Oct 2023 Chirlmin gives a talk in Wageningen University
Oct 2023 Yorick starts his internship
Sep 2023 Archana and Chirlmin participate Marie-Curie annual workshop in Genoa
Aug 2023 Group retreat!
Aug 2023 Chirlmin gives keynote speech in EKC 2023
Aug 2023 Jieun starts her internship in Ewha
Jul 2023 Chirlmin gives a talk in European Biophysical Society
Jul 2023 Maya starts her summer internship
Jun 2023 Beray starts his Erasmus+ internship
Jun 2023 Sung Hyun receives Outstanding Scientists fellowship from Korea
June 2023 Mike received Kavli Synergy grant
Jun 2023 Chirlmin gives a talk in VU Amsterdam
Jun 2023 Chirlmin gives a talk in Radboud UMC
Jun 2023 Chirlmin gives a talk in Univ of Munster, Germany
May 2023 Yugyeong from Sang Wook Lee's lab visits us for HFSP collaboration
Apr 2023 Dae Sung Yoon from Korea Univ visits us for ERC-Korea collaboration
Feb 2023 Sung Hyun/Chirlmin's proposal accepted by National Research Foundation of Korea
Feb 2023 Meryem starts her internship
Feb 2023 Sung Hyun gives a talk in BPS
Feb 2023 Chirlmin's interview with Precision Medicine published
Feb 2023 Sinan starts his master project
Feb 2023 Amina starts her master project
Jan 2023 Archana starts her PhD study
Jan 2023 Chirlmin organizes Biophysics Korea-Europe 2023 in Seoul
Jan 2023 Jiyoon starts her internship in Ewha
Jan 2023 Dong Hoon/Sung Hyun's paper accepted in iScience
Jan 2023 Jack starts his faculty position in Utrecht University
See also news in 2011- 2022
Lab protocols (internal use)
Research practicum (Applied Physics)