CHIRLMIN JOO LAB
- Using cutting-edge single-molecule fluorescence tools, we investigate how small regulatory RNA mediates gene silencing (RNA interference) and anti-viral defense (CRISPR immunity and beyond). We apply the mechanistic understanding to genome editing.
- We develop single-molecule protein sequencing techniques for advanced proteomics analysis. We organized conferences in 2017 and 2019.
- Kim, Loeff, Colombo, Jergic, Brouns, Joo "Selective loading and processing of prespacers for precise CRISPR adaptation" Nature (2020)
- Cui, Klein, Hegge, Chandradoss, van der Oost, Depken, Joo "Argonaute bypasses cellular obstacles without hindrance during target search" Nature Communications (2019)
Globyte, Lee, Bae, Kim, Joo "CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion" EMBO Journal (2018) Restrepo, Joo, Dekker "Paving the way to single-molecule protein sequencing" Nature Nanotechnology (2018) van Ginkel, Filius, Szczepaniak, Tulinski, Meyer, Joo "Single-molecule peptide fingerprinting" PNAS (2018)
| | LAB NEWS
September 2020 Raman starts a master project July 2020 Tygo defenses his bachelor thesis
July 2020 Pim defenses his master thesis
June 2020 Roy defenses his master thesis
May 28, 2020
April 2020 Sungchul's paper accepted by Nature Communications
April 2020 Mike's paper published in Angewandte Chemie
March 2020 Mike•Thijs•Margreet's paper published in Nano Letters
February 2020 Our Cas1-2 work highlighted by TU Delft (News)
February 2020 Sungchul•Luuk•Sabina's paper published in Nature
February 2020 Tygo starts a bachelor project
February 2020 Taekjip (TJ) Ha gives a Kavli Colloquium talk
January 2020 Woo-Chan joins as a visiting scholar
January 2020 Laura starts her position in Vintura
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