* corresponding authorship See also papers we published as contributing authors § equal contribution M. Filius, S. H. Kim, I. Severins, C. Joo, "High-Resolution Single-Molecule FRET via DNA eXchange (FRET X)", (BioRxiv) M. Klein, T. J. Cui, I. MacRae, C. Joo*, M. Depken*, "Skipping and sliding to optimize target search on protein-bound DNA and RNA", (BioRxiv) K. H. Park § § "Tetrameric architecture of phenol-bound DmpR, a single-component AAA+ ATPase transcriptional regulator", Nature Communications (2020) (open access) § § S. Kim §,* § - Featured content for Nobel Prize in Chemistry 2020 - Highlighted in CORDIS - Highlighted in The CRISPR Journal - News in TU Delft L. Restrepo-Pérez, C. H. Wong, G. Maglia, C. Dekker*, C. Joo*, "Label-free detection of post-translational modifications with a nanopore" Nano Letters (2019) (open access) T. J. Cui, M. Klein, J. W. Hegge, S. D. Chandradoss, J. van der Oost, M. Depken*, C. Joo*, "Argonaute bypasses cellular obstacles without hindrance during target search" Nature Communications (2019) (BioRxiv, open access) L. Restrepo-Pérez, G. Huang, P. Bohländer, N. Worp, R. Eelkema, G. Maglia, C. Joo*, C. Dekker* "Resolving Chemical Modifications to a Single Amino Acid within a Peptide Using a Biological Nanopore" ACS Nano (2019) (open access) T. J. Cui, C. Joo*, "Facilitated diffusion of Argonaute-mediated target search" RNA Biology (2019) (free access) - Editorial in RNA Biology L. Loeff, C. Joo*, "Biophysics of RNA-guided CRISPR immunity", Springer, (2019) (book chapter) S. Zhao § § V. Globyte § § - Highlighted in EMBO Journal L. Restrepo-Pérez, C. Joo*, C. Dekker* "Paving the way to single-molecule protein sequencing" Nature Nanotechnology (2018) (paper) (open access) V. Globyte, S. H. Kim, C. Joo*, "Single-molecule view of small RNA-guided target search and recognition" Annual Review of Biophysics (2018) (open access) L. Loeff, S. J. J. Brouns*, C. Joo* "Repetitive DNA reeling by the Cascade-Cas3 complex in nucleotide unwinding steps" Molecular Cell (2018) (paper) (bioRxiv) - News in TU Delft (Cas3: a fishing rod and a shredder rolled into one) J. van Ginkel, M. Filius, M. Szczepaniak , P. Tulinski , A. S. Meyer*, C. Joo* "Single-molecule peptide fingerprinting" Proceedings of the National Academy of Sciences (2018) (paper) (bioRxiv) (YouTube) M. Fareh, J. van Lopik, I. Katechis, A. W. Bronkhorst, A. C. Haagsma, R. P. van Rij*, C. Joo* "Viral suppressors of RNAi employ a rapid screening mode to discriminate viral RNA from cellular small RNA" Nucleic Acids Research (2017) (open access) S. M. Klum § § L. Restrepo-Pérez § § § § § C. Joo*, & J. van der Oost* "Autonomous generation and loading of DNA guides by bacterial Argonaute" Molecular Cell (2017) (paper) (PMC free text) M. Klein § § M. Fareh, K. H. Yeom, A. C. Haagsma, S. Chauhan, I. Heo, & C. Joo* "TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments" Nature Communications 7:13694 (2016) (open access) N. T. Schirle, J. Sheu-Gruttadauria, S. D. Chandradoss, C. Joo*, & I. J. MacRae* “Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.” eLife 4:e07646 (2015) (open access) Y. Yao, M. Docter, J. van Ginkel, D. de Ridder*, & C. Joo* "Single-molecule protein sequencing through fingerprinting: computational assessment" Physical Biology, 12(5):055003 (2015) (open access) (data) S. D. Chandradoss, N. T. Schirle § § B. Kim§, M. Ha§, L. Loeff§, H. Chang, D. K. Simanshu, S. Li, M. Fareh, D. J. Patel, C. Joo*, & V. N. Kim* "TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms" EMBO Journal, 34(13):1801-15 (2015) (open access) T. R. Blosser§, L. Loeff§, E. R. Westra, M. Vlot, T. Kunne, M. Sobota, C. Dekker, S. J. J. Brouns*, & C. Joo* "Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex" Molecular Cell, 58(1):50-60 (2015) (paper) (PMC free text) C. Joo*, M. Fareh, V. N. Kim "Bringing single-molecule spectroscopy to macromolecular protein complexes" Trends in Biochemical Sciences, 38(1):30-37 (2013) (paper) (PMC free text) K. H. Yeom, I. Heo, J. Lee, S. Hohng, V. N. Kim*, & C. Joo*, "Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation" EMBO Reports, 12, 690-696 (2011) (paper) (PMC free text) KEY PROTOCOLS M. Fareh & C. Joo "Probing RNA-Protein Interactions with Single-Molecule Pull-Down Assays" Methods in Molecular Biology, 1814:267-285 (2018) (PDF) M. Fareh, L. Loeff, M. Szczepaniak, A. C. Haagsma, K. H. Yeom, C. Joo* "Single-molecule pull-down for investigating protein—nucleic acid interactions" Methods, 105:99-108 (2016) (PDF) (PMC free text) - Published in a special series of Single-molecule probing by fluorescence and force detection S. D. Chandradoss, A. C. Haagsma, Y. K. Lee, J. H. Hwang, J. M. Nam, & C. Joo* "Surface passivation for single-molecule protein studies" Journal of Visualized Experiments, (86), e50549, doi:10.3791/50549 (2014) (open access) BOOKS C. Joo and D. Rueda, “Biophysics of RNA-Protein Interactions: A Mechanistic View” Springer, 2019 (online) PATENTS C. Joo, C. Dekker, H. G. T. M. van Ginkel, A. S. Meyer, Single-molecule protein sequencing, WO2014014347 |